Struggling Rayo win at Valladolid after late penalty save
Ronaldo returned from his lavish Valentine's Day engagement party in Paris with an injury to his toe.
Napoli went down 3-1 at home to RB Leipzig, Arsenal and AC Milan enjoyed comfortable away wins, and Borussia Dortmund's Michy Batshuayi scored twice to secure a 3-2 victory in Europa League last 32, first leg action
Barcelona kept up the pressure on La Liga title rivals Atletico Madrid and Real Madrid when Lionel Messi struck from the penalty spot in a 1-0 win at Espanyol in Saturday's Catalan derby.
The Premier League champions signed Athletic Bilbao left back Asier del Horno for $14.50 million on a three-year contract.
India held off a later rally by the Dutch to win their opening match in the four-nation junior hockey tournament in Spain.
Atletico Madrid secured a berth in the Champions League group stage for next season and Deportivo La Coruna narrowly escaped relegation when they came from two goals down to draw 2-2 at champions Barcelona on the final day in La Liga on Saturday.
Marcelino dismissed but Valencia keep pressure on Barcelona
One of the most disappointing aspects of Barcelona's failure to win major silverware last season was the lack of on-field chemistry between Lionel Messi and Neymar.
New UEFA president Aleksander Ceferin believes London is the perfect choice to stage the climax to Euro 2020 after 12 other cities across the continent host earlier matches, he said on Wednesday.
Former Barcelona great Michael Laudrup lambasted the Brazil international for "provoking" the opposition in Saturday's 5-1 win at Leganes and Neymar's flamboyant style will be scrutinised again on Wednesday when Barcelona host Atletico.
Real Madrid coach Carlo Ancelotti is confident Cristiano Ronaldo's three-match ban will be reduced to two so he can play in Saturday's La Liga game at home to Elche.
The Portuguese can expect a hostile reception in Valencia, who had to suffer 15 of his goals for Real Madrid and are returning to the Champions League for the first time in three years.
10-man Real Madrid fought back from a goal down to claim a 3-1 win at home to Athletic Bilbao.
Barca must beat Villareal on the weekend if they are to stand a chance of overhauling Real in the run in.
Images from the Champions League matches played across Europe on Wednesday.
India beat Spain 3-2 to record their second successive win in the junior hockey tournament in Spain
Five-time world champion Viswanathan Anand suffered a shocking loss against Sergey Karjakin of Russia in the fourth round of Candidates Chess tournament.
Real Madrid midfielder Gareth Bale damaged a calf muscle in his left leg during Tuesday's 4-0 Champions League Group A victory at home to Shakhtar Donetsk, tests confirmed on Thursday.
Barcelona shook off the disappointment of their Champions League defeat by Chelsea to extend their lead in the Primera Liga to 11 points with a 2-0 defeat of Athletic Bilbao.
Real Madrid president Florentino Perez has blamed Manchester United's "lack of negotiating experience" for the failure of goalkeeper David De Gea's move to the Spanish capital on Monday.
News of all that's transpired on and off the football field
Chelsea's Marcos Alonso and Real Madrid's Nacho were notable absentees in defence, along with Atletico Madrid midfielder Koke.
They beat Athletic Bilbao 4-0 at the Bernabeu on Thursday to make the grade.
Winning the treble last season has spurred Barcelona to try and win all six trophies up for grabs this year and replicate the feat they achieved in 2009, midfielder Andres Iniesta said on Monday.
The Bavarians have now won the German league title a record 29 times.
Real fought back after a calamitous own goal from keeper Keylor Navas gave Betis the lead in the 25th minute, just after the Costa Rican escaped a possible red card. Cristiano Ronaldo pulled the hosts level in the 41st with a diving header.
'I haven't lost any strength in the last four days and in one sense I feel a little relieved but focused on the objectives we set for ourselves at the start of the season'
Real Madrid coach Zinedine Zidane shrugged off his first setback since taking over from the sacked Rafa Benitez after his new team could only manage a 1-1 draw at Real Betis in La Liga.
AC Milan, Villarreal and Nice reached the knockout stage of the Europa League after posting wins on Thursday in the penultimate round of the group stage.
Here are five talking points from the weekend's action:
Real Madrid coach Zinedine Zidane is under pressure to break up his misfiring attacking trio of Cristiano Ronaldo, Karim Benzema and Gareth Bale when he takes the La Liga leaders to Alaves on Saturday.
Barcelona are in the middle of an injury crisis as they head to Valencia for Saturday's La Liga game looking to keep up with pacemaking pair Atletico Madrid and Real Madrid. Without injured goalkeeper Jasper Cillessen and right back Sergi Roberto for the last two games, Barca will also be missing defenders Jordi Alba and Gerard Pique after both were hurt in Wednesday's 4-0 win over Manchester City in the Champions League. Pique sprained his right ankle while Alba injured his left hamstring and both are out until November.
Jose Callejon took advantage of Napoli's numerical advantage in the 48th minute of the playoff round second leg tie, handing them an away goal which, added to their 2-0 win from the first leg, effectively ended Nice's challenge as it left the French side needing to score four goals.